Senior Scientist- Functional Genomics
Job title: Senior Scientist- Functional Genomics in San Francisco, CA at Amgen
Company: Amgen
Job description: Career Category ResearchJob DescriptionJoin Amgen’s Mission of Serving PatientsAt Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Senior Scientist- Functional GenomicsWhat you will doLet’s do this. Let’s change the world. In this vital role you will join an enthusiastic, fast-paced team utilizing cutting edge ‘omics and cellular profiling technologies to advance target discovery and progression across Amgen’s therapeutic areas.
Expected salary: $135882 - 160726 per year
Location: San Francisco, CA
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Company: Amgen
Job description: Career Category ResearchJob DescriptionJoin Amgen’s Mission of Serving PatientsAt Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Senior Scientist- Functional GenomicsWhat you will doLet’s do this. Let’s change the world. In this vital role you will join an enthusiastic, fast-paced team utilizing cutting edge ‘omics and cellular profiling technologies to advance target discovery and progression across Amgen’s therapeutic areas.
- Conduct impactful high throughput screening and profiling approaches for target discovery
- Help identify and implement new technologies to accelerate discovery
- Develop and execute downstream mechanistic assays to validate and advance targets
- Collaborate closely with disease area, computational biology, and therapeutic development teams to make actionable decisions as a technical and intellectual subject matter expert
- Present research findings to cross-functional groups at internal and external meetings and publish scientific findings in peer-reviewed forums
- Doctorate degree in genetics, genomics, cell and molecular biology, systems biology, or related disciplines
- Demonstrated track record of independent critical thinking, complex problem solving, and innovative research, evidenced by significant contributions to discovery programs and publications in top tier journals
- Hands-on expertise conducting and delivering complex screening campaigns for discovery
- Proficiency with experimental design, data generation, and analysis principles across a broad range of technologies and assays including transcriptomics, imaging, and cytometry
- Expertise with molecular and cell biology tools such as antibodies, CRISPR, overexpression constructs, lentivirus, various approaches for cell engineering
- Experience with genomic perturbation at scale using cell lines and primary cells
- Proficiency in programming (e.g. in R/Python), Unix/Linux environments, and cloud computing environments for the analysis of large omics datasets and generation of custom computational pipelines
- Strong written, verbal, and oral communication skills and ability to thrive in cross-functional settings
- Experience in managing and coordinating team efforts
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models, including remote and hybrid work arrangements, where possible
Expected salary: $135882 - 160726 per year
Location: San Francisco, CA
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